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Ondansetron for antinausea for Bella (feline with CKD)

DayshaG

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I had to bring Bella to the ER vet a few weeks ago due to dehydration and vomiting. I also am working with Hana Makinen for animal communication and end of life aspects of things, as well as Gail Pope. The big ❓ in my mind is always "how much times does she have?". Nobody has that answer, I know. It has been an emotional roller coaster! I am looking into other ways to support Bella as she continues to have nausea (confirmed specifically with Hana, and this has been a long running thing since she was diagnosed with kidney disease 4 years ago). I have also started to have a mobile vet come to the house to give subcutaneous fluids, I was hoping twice a week though the vet texted me and said may need to get it once a week. I am not sure we are at that frequency yet, she has good days and bad days. It is just that the bad days make me feel stressed, even though you all have been GREAT in helping me come from a place of love instead of fear, sometimes as this progresses... I just feel scared. It is also triggering memories of my husband's physical decline before he passed not 2 years ago.

My questions for you is about Ondansetron. It was given to her by the ER vet. Along with Cerenia which the taste of that she ends up spitting out, and always has. But I see Ondansetron can cause constipation. Before I read this, I started adding canned plain pumpkin back to Bella's food this AM to help her in that regard. She has started over grooming again and has puked up hair balls over the weekend. If we are talking about palliative care, my friend who uses homeopathy, herbs, and western medicine suggested giving her whatever makes her comfortable. What are your thoughts on this drug, as well as how to ease any constipation.

Also, CBD. I contacted a company recommended by Gail and had a positive experience though didn't make any purchases yet. The vet tech I spoke to suggested Ondansetron as well. I wanted to look further into studies but again, my friend suggested since this is all palliative, give her what will make her more comfortable. I have also been working with my homeopathic vet Dr. Herman.

What is your experience on CBD with cats? Bella does have arthritis as well. Her creatinine also had dropped since Sept 2025 to 2.71.
 
P.S. It seems my vet offers a variety of methods to get Ondansetron, including transdermal gel. Thoughts?
 
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