Lyme Nephritis and C6 of 748

Dr. Jeff

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Hi @everyone-

Many of you know that my pup Vanya passed away from protein (albumin) loss in her urine, from kidney dis-ease associated with Lyme, last Friday night.

On Saturday, I had a full blood test panel run on my other pup, Archie.

Unfortunately, his blood albumin is also borderline low and his Lyme antibody (C6) is as super high at >748!

It's possible that his low blood albumin is from intestinal loss from the chronic diarrhea he's had off and on since I got him.

But before I decide what to do next, I want to rule out Lyme kidney dis-ease, like with Vanya.

When my urine dipsticks arrive, I'll do a home screening check for protein in his urine.

If it is positive, then I'll also quantitate the protein loss by catching a morning urine and running a protein:creatinine ratio at the lab. No matter what the result is, it will be his baseline.

The UPC will also help provide lab confirmation and further context for deciding whether to disrupt his microbiome with the anti-biotic doxycycline.

In the meantime, I am focusing on maximizing his therapeutic engagement, happiness and supportive supplements.

I have not modified his diet. The last few were mainly raw meat (Rawganics), blueberry-kale, sauerkraut and some Farmers Dog cooked fresh food.

In addition to his homeopathic medicine, he's taking SmartZYME DHA, LD Support, VRS TruHepato liver and energy support, an individualized flower essence blend, and Xymogen Probio and CoqMaxOmega:

Lyme supplements.JPG

Fortunately his BEAM is almost 100% and he seems to be loving his extra engagement, walks, hugs and treats!


I'll update this thread as Archie's Lyme story unfolds.
 

novasimpson

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Thank you for sharing all this information Dr Jeff! Lots of loving energy being sent to Archie ❤❤

Should c6 be checked regularly with labs? Toshi had ?signs of ?chronic lyme like shifting lameness...I wonder if we should of had her c6 tested earlier? I think it was in the 200s when we checked (after her other labs indicated Lyme nephritis).

Would you/when would you consider using doxycycline? From what I have learned in people, doxycycline helps more as an anti-inflammatory with Lyme and so question if it is really ever needed? But in dogs is it known to help prevent Lyme nephritis or lameness?
 

Julie W.

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This is a great thread. I look forward to reading more. My dog Logan had very high lyme and his BEAM was normal.
 

Dr. Jeff

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You're welcome Nova, and yes this is a difficult but important question Julie.

Wonderful questions about monitoring C6 and using doxycycline, Nova!

The answers depend on the context of the pet.

In asymptomatic cases where you are deciding what to do, yes monitoring C6 every 3-6 months can be useful. Even more sensitive and specific would be to do the Cornell Multiplex test a few times/year.

Less frequent monitoring may be indicated for pets who are already sick. Here, there are already enough symptoms to monitor. C6, Multiplex or any other test result is just one of the internal and external symptoms that help decide what to do.

Regarding my next steps for Archie, I am doing HMDM Step 2 (research and information collection).

I have an internal medicine consultation set up for today and will be checking his urine for protein loss as well as either doing a C6 or Multiplex for confirmation this week.

Regardless of what I decide to do, I feel very appreciative that he is continuing to love his extra engagement, including walks, play sessions and therapeutic touch every few hours.
 

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