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Buddy Boston Terrier's brain cancer

Dr. Jeff

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YW Ann. Thanks for taking such great care of Buddy. 😍 :snowman::dog2:
 

AnnS

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Dr. Jeff, I just went in and reenabled notifications. I guess if you log out, you have to reenable. It's likely I logged out at some point. I hope I start receiving them again!

Actually, I do get Alerts on the website, but I haven't been receiving the email notices, like about upcoming webinars and notices that it's time to schedule a vet consultation, things like that. I didn't see a reply in Spam from HA.
 

AnnS

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hi again!
The town will not refuse us the parvo vaccine, as the clerk I spoke with said it is not a state law, but a city ordinance. So I can get Buddy his updated tag. These little things seem to mean a lot, because they are what we have always done, and it helps me feel like this is life as usual (I know this is denial -- or should I say hope!).

Have an enjoyable nearly summer weekend, everyone! And a Happy Father's Day to the men out there! :)
 

AnnS

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@Dr. Jeff
hi Dr. Jeff! I hope you are well!
We have had our ups and downs these past two months! Buddy's prednisone was increased last month as a first step in stopping the seizures he was having regularly in May. The "petit mal" didn't stop, and he got diarrhea twice in about a month, pretty bad. Both times he was taken off prednisone until the diarrhea was well resolved with antibiotic and probiotic. He is back on until we see the neurologist on July 1. Since the upped dose of prednisone didn't take the seizures away (but an additional seizure med did -- nearly 26 days seizure-free!), I will discuss with the vet going back to the 2.5mg daily dose that he dropped us to in April. In the meantime, I am wondering about holistic helps for inflammation of the brain? I am giving Buddy daily probiotic, glucosamine, and sardines often when his digestive system allows! I seem to have picked up that resveratrol is good for brain tumor inflammation, omega 3's, vit C, certain mushrooms. I would like to start him on some anti-inflammatory supplements before our vet visit. I can't do them all, but which do you think would be most helpful for inflammation around a brain tumor. He did seem to be rubbing his head, shaking it, pawing at it when off prednisone. I know there is controversy surrounding prednisone, but I am trying to do the best I can for Buddy. If there are supplements that would work for him, maybe we can wean him off prednisone in time.

As always, thank you so much!

Ann & Buddy
 

Dr. Jeff

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Hey Ann!

I'm sorry for the rocky road and challenging symptoms of the past few months.
holistic helps for inflammation of the brain?
Perhaps look at dimethylyglycine. It is also shown to decrease seizures by raising the seizure threshold.

most helpful for inflammation around a brain tumor.
Perhaps just keep doing what you're doing, add in DMG and see about reducing the steroid?
 

AnnS

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Thank you, Dr. Jeff!
I just ordered it on Amazon. By the way, I used the probiotic spray you recommended when Buddy had the skin eruptions (prednisone-induced!:rolleyes3:) in April for another application. It was very soothing for his rear when he had the loose stools. I would apply it with a soft compress twice daily. So thanks for all the great leads!:)
 

AnnS

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hi Dr. Jeff--

Buddy had three seizures this past day.😔 He had gone 33 days without any obvious seizure, as far as I know. These were all "grand mal," but I think he has had worse, or maybe I am getting used to seeing them. He barks for hours afterwards, off and on. He is barking now. Walks can help, and chew bones have helped, but he didn't want his bone today, and it is stormy in CT (as you probably know!), not great weather for a walk. Actually, I just gave him a chew bone, and he is occupied with it and not barking at the moment!

Tomorrow will be a week since I started him on DMG. It says to give suggested level twice per day for two weeks, then give once per day. 21-40 lb: give 1ml. Buddy weighed 22.9 last I checked. I have only been giving him 0.5ml, as he is on the lower end of that weight spectrum. Is this a good amount for Buddy at this stage: on phenobarbital, keppra, and prednisone, which I hope we can cut back. We see the neurologist tomorrow.

The barking is very difficult to endure. He is very agitated, not himself. His eyes don't look like him, and he does not want to be touched, but will jump away. When his brain settles down, I guess, he is back to Buddy. I have a lot of essential oils that I haven't been using. Do you think they would help?

Thanks so much!

Ann & Buddy
 

Dr. Jeff

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I'm. super sorry Ann to hear about Buddy's latest seizures.
Is this a good amount for Buddy at this stage
Yes. .5ml twice a day is good.

The barking is very difficult to endure
Yes.

I just gave him a chew bone, and he is occupied with it and not barking at the moment!
That's exactly the best strategy (either a bone, a walk or whatever makes him happiest).

Do you think they would help?
Yes, they absolutely could.
 

AnnS

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@Dr. Jeff
Good morning, Dr. Jeff!
Buddy saw the neurologist on Monday. They have put him on another seizure med, zonisamide. He had a grand mal seizure as we were walking out the door after our appointment, and they whisked him in, thinking we were arriving for an emergency, not realizing we had already been seen. So he was given the "cluster buster" drug and an anti-nausea drug. He has been sleeping constantly since, and both nights after didn't budge to sleep with us. And he has been refusing food, which has never happened in his life. I have been trying to get him to eat with enticing toppers, but his appetite is not its hearty self. It seems odd to me that this would happen so abruptly right after being at the vet's office. I know the new drug suppresses appetite, but I believe he refused at least part of his dinner before getting his first dose. Now they want to give him Entyce, which I told them to hold at the desk as we try getting him to eat in a more natural way. Do you have any opinion on Entyce?

If that seizure had happened on the way home, we would have dealt with it as we have been doing, but because they thought we were arriving and not leaving the hospital, they gave him that drug to stop seizures which I believe is like Xanax. Would that cause him to be so sleepy for going on two days? And he was nauseous during that incident, I don't know why. Would that be why he is not eating now? The vet said try Entyce, and if that doesn't work, he will work with the meds. Buddy IS eating with enticing toppers, just not as heartily and as much as he always has. Does a dog with a glioma eventually lose his appetite? Or maybe this all has to do with the unfortunate incident at the vet? Or maybe the new med? I would never pit one vet against another, but asking helps me understand and chart our course forward.

Thank you for your support, and for being a valued member of "Team Buddy!"

Ann & Buddy
 

Dr. Jeff

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I'm sorry that Buddy needed the "cluster busters" and am glad you were at the neurologist when this happened.
Do you have any opinion on Entyce?
It's fine.

Would that cause him to be so sleepy for going on two days?
It could, yes.

Does a dog with a glioma eventually lose his appetite?
Yes. And they commonly can have alterations in appetite, likes and dislikes. Along with the structural changes in the brain, lots of things can change in his life, BEAM, etc.

IMHO, the best strategy is still to focus on optimizing the frequency of Buddy's joy and happiness throughout the day.

Perhaps also let him sleep outside in the fresh air, healing sun and in contact with mother earth. She will absolutely help his body do the best it can do.
 

AnnS

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hi Dr. Jeff!
I hope you had a fun 4th of July!

Buddy isn't exceedingly sleepy anymore, and his appetite seems pretty much back to normal. We let him have a "pup cup" ice cream last night, even though I know sugar is an absolute NO!!! for cancer. It's a bucket list item, only this once! He does seem more finicky about what he eats or doesn't eat, but we can work with that.

Yes, his BEAM has changed. I will work on this, as well. We tried to walk yesterday, but Buddy was having a difficult time breathing. We took long rests, and he pushed himself, but I had to carry him to the car after 3/4 mile. I thought the walk would distract from his agitated barking (which he is doing right now!). Buddy has loved sleeping outside in the sun during the summer, but this year he comes in very quickly when he goes out. I will try sitting out there with him.

When I can walk him I will. And chew bones do help for the duration of the chew. I have asked this question before, but that was when he was on two seizure meds. Now he is on pheno, keppra, zonisamide. When he is getting beside himself barking, can I use CBD on top of all these strong drugs, not to mention prednisone? I have succumbed on one or two occasions, but only gave 1/4 of 1 mg. I believe he can have a mg for his size. It would be a good tool to have in my arsenal, as he is doing a lot of barking lately.

Thank you for your kind support, Dr. Jeff!

Ann & Buddy
 

Dr. Jeff

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When he is getting beside himself barking, can I use CBD on top of all these strong drugs, not to mention prednisone?
Yes! And you can safely give a much higher dose of the CBD.

The main "downside" is that he may fall asleep!💤💤💤
 

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